Xenosaga: The Animation

The year is T.C. 4767. Humanity fled Earth four thousand years ago, and now faces extinction at the hands of a hostile alien race called the Gnosis. In a desperate effort to survive, Vector engineer Shion Uzuki develops KOS-MOS, a highly advanced android designed to combat the threat. But when the Gnosis destroy their ship, Shion and her allies are caught in a conflict where the lines between friend and foe blur.